_{Flights to South America – Please note: Many or all of the products featured here are from our partners, who compensate us. This may influence which products we write about, as well as where and how they appear on a page. However, this does not influence our evaluations. Our opinions are our own.}

With its lush rainforests, towering peaks, vibrant cities, and ancient ruins, South America offers one of the most dynamic travel experiences on the planet. Whether you’re planning to explore Patagonia, dive into Brazilian beaches, or hike the Inca Trail, TravelUp can help you find affordable flights to get you there.

Why Use TravelUp to Book Flights to South America?

South America’s geography makes efficient routing essential—and prices can vary widely based on origin, season, and carrier. TravelUp’s intuitive flight search platform allows travelers to:

• Compare airfare from global and regional airlines
• Filter by stops, departure time, airline, and cabin class
• Build custom itineraries using one-way or multi-city tools
• View pricing across a flexible date calendar to find the best fares

Whether you’re traveling from the U.S., Canada, Europe, or another region, TravelUp helps you save on long-haul flights to Latin America’s top destinations.

Top South American Destinations You Can Book Through TravelUp

TravelUp offers access to major cities and gateways across the continent, including:

• São Paulo & Rio de Janeiro, Brazil – Brazil’s largest cities are cultural powerhouses with iconic beaches and festivals.
• Buenos Aires, Argentina – Known for tango, architecture, and world-class steak.
• Lima & Cusco, Peru – Perfect for foodies and history buffs headed to Machu Picchu.
• Bogotá & Medellín, Colombia – Rising stars on the travel scene, combining modernity with natural beauty.
• Santiago, Chile – A cosmopolitan capital surrounded by mountains and wine country.
• Quito, Ecuador – Gateway to the Galápagos and the Andes.

TravelUp also covers smaller airports in destinations like Iguazú Falls, Mendoza, and Cartagena—ideal for travelers looking to go beyond the main cities. Learn more.

Smart Booking Tools for South America Travel

South America-bound flights often involve connections. TravelUp’s tools help optimize your route with:

• Flight duration filters and nonstop-only options
• Ability to sort by price, time, or airline preference
• Flexible dates to find off-peak pricing
• Fare alerts so you can book when prices drop

TravelUp supports both major international carriers like LATAM, Avianca, Copa Airlines, American Airlines, and Delta, as well as budget airlines serving domestic and regional routes.

Bundle Flights + Hotels for Added Savings

From Amazonian eco-lodges to urban boutique hotels in Bogotá or beachfront resorts in Florianópolis, TravelUp offers a wide range of accommodations across South America.

By booking flights and hotels together, you’ll often unlock extra discounts and exclusive promotions, helping you stretch your travel budget further. Each listing includes detailed descriptions, real guest reviews, and high-quality images to help you make confident choices. Learn more.

Why Visit South America in 2025?

South America is emerging as one of the top travel regions for 2025, thanks to its affordability, expanding tourism infrastructure, and visa policy reforms in countries like Brazil and Argentina. With direct flights increasing and traveler interest surging, now’s the time to plan your trip. Learn more.

TravelUp’s global flight network and real-time pricing make it an ideal platform to explore this vast and exciting continent.

---

Travel Tip:
Try flying into one hub (like Lima or São Paulo) and out of another (like Buenos Aires or Bogotá) to see more of South America without backtracking. Use TravelUp’s multi-city booking feature to simplify the process.

---